League Two outfit Cambridge United will play what is surely their biggest game of the season so far on Friday night when they host Manchester United in the FA Cup fourth round.

The U's head into the match as overwhelming underdogs, but three consecutive wins in all competitions mean that Richard Money's side will be full of confidence.

Cambridge, who sealed their progress in the last round thanks to a 2-1 victory over Luton Town, have reached the quarter-finals of the competition twice before.

Meanwhile, Louis van Gaal's United saw off Yeovil Town 2-0 in the third round thanks to goals from summer signings Ander Herrera and Angel di Maria.

The Red Devils currently sit in fourth place in the Premier League table following three victories, two draws and a defeat in their last six outings. They returned to winning ways last weekend with a 2-0 triumph at Queens Park Rangers.

With a number of first-team players returning to fitness for a busy second half of the season, Van Gaal is likely to rest a handful of key names for the trip to Cambridge.

Victor Valdes is reportedly in line to make his debut in goal for United, while the likes of Paddy McNair and Jonny Evans may also feature.

James Wilson could be handed a start up front for the visitors after scoring against QPR last weekend. However, Rafael, Ashley Young and Robin van Persie are all due to miss out through injury.

Cambridge:

Form in FA Cup: WDWW
Form in all competitions: DLLWWW

Possible starting lineup: Dunn; Tait, Nelson, Coulson, Taylor; Hughes, Champion, McGeehan, Donaldson; Elliott, Kaikai

Man Utd:

Form in FA Cup: W
Form in all competitions: WDDWLW

Possible starting lineup: Valdes; Smalling, Evans, McNair, Shaw; Valencia, Fellaini, Fletcher, Januzaj; Wilson, Rooney

Sports Mole says: 0-2