Manchester United manager Erik ten Hag will be without the suspended Bruno Fernandes for Tuesday's EFL Cup quarter-final with Charlton Athletic at Old Trafford.
The Portuguese playmaker has picked up two yellow cards in two matches at the tournament so far, leaving Ten Hag with something of a midfield quandary amid the absence of Donny van de Beek with his knee issue.
Axel Tuanzebe also continues to work his way back from a long-term problem, while Jadon Sancho is undergoing his individual programme, with no timeframe placed on the Englishman's return.
Loan signing Jack Butland could be handed his debut in goal for the Red Devils after arriving from Crystal Palace, possibly with a new-look backline of Victor Lindelof and Harry Maguire.
Aaron Wan-Bissaka can also feel optimistic of coming in at right-back, with Tyrell Malacia holding his place on the left as Ten Hag looks towards Saturday's Manchester derby with Manchester City.
Casemiro is in line for a rest, giving Fred and Scott McTominay the green light to join Christian Eriksen, who should be the most advanced of the midfield trio with Fernandes and Van de Beek out of contention.
Anthony Elanga and Alejandro Garnacho can feel confident of earning starts in the wide areas, likely with Anthony Martial continuing in the number nine position as he aims to consign his injury woes to history.
Man United possible starting lineup: Butland; Wan-Bissaka, Lindelof, Maguire, Malacia; Fred, McTominay, Eriksen; Elanga, Martial, Garnacho body check tags ::