The Theatre of Dreams is the venue for the first Manchester derby of the season, as Manchester City make the short trip to square off with bitter rivals Manchester United in Sunday afternoon's headline Premier League contest.
Erik ten Hag's side overcame Copenhagen 1-0 in their midweek Champions League battle, while the treble winners put BSC Young Boys to the sword 3-1, and here Sports Mole rounds up the team news for both clubs.
MANCHESTER UNITED vs. MANCHESTER CITY
MANCHESTER UNITED
Out: Jadon Sancho (disciplinary), Lisandro Martinez (foot), Luke Shaw (muscle), Amad Diallo (knee), Tyrell Malacia (knee)
Doubtful: Casemiro (ankle), Aaron Wan-Bissaka (thigh)
Sports Mole's predicted XI: Onana; Dalot, Varane, Maguire, Reguilon; Casemiro, Eriksen; Antony, Fernandes, Rashford; Hojlund
MANCHESTER CITY
Out: Manuel Akanji (suspended), Kevin De Bruyne (hamstring)
Doubtful: None
Sports Mole's predicted XI: Ederson; Walker, Stones, Dias, Gvardiol; Rodri, Silva; Doku, Alvarez, Foden; Haaland
For data analysis of the most likely results, scorelines and more for this match please click here.
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