Middlesbrough boss Aitor Karanka has made three changes to the side that beat Bolton Wanderers 2-1 in midweek for the visit of Sheffield Wednesday.
Seb Hines, Emilio Nsue, and Adam Clayton drop out while summer signing Kike continues up top against the Owls in the Championship this afternoon.
Meanwhile, new signing Stevie May is handed a start up front for Wednesday as they look to extend their unbeaten run.
Middlesbrough: Mejias; Damia, Ayala, Omeruo, Friend; Reach, Leadbitter, Whitehead, Adomah; Tomlin, Kike
Sheff Wed: Westwood; Mattock, Loovens, Semedo, May; Palmer, Nuhiu, Maguire, Coke; Lees, Maghoma