Millwall make five changes to the side that drew with Sheffield Wednesday in midweek, with Mark Beevers, Josh Wright, Shaun Williams, Liam Feeney and DJ Campbell in for Shane Lowry, Nicky Bailey, Liam Trotter, Lee Martin and Andy Keogh.
Campbell makes his full debut for the club after coming off the bench to score against Wednesday.
Reading, meanwhile, are unchanged for the fourth successive game having beaten Blackpool 5-1 on Tuesday.
Millwall: Bywater; Fredericks, Shittu, Beevers, Malone; Woolford, Wright, Williams; Feeney, Morison, Campbell
Reading: McCarthy; Gunter, Obita, Gorkss, Pearce; Akpan, Williams, McCleary, McAnuff; Le Fondre, Pogrebnyak