Olympiacos manager Marco Silva has made one change to the side that beat Dinamo Zagreb in the reverse fixture a fortnight ago.
Hernani replaces Felipe Pardo in Silva's solitary alteration from the 1-0 victory.
Zagreb boss Zoran Mamic follows suit, with a single change to his team for their trip to the Georgios Karaiskakis Stadium.
Marko Pjaca comes into an attacking midfield position in place of El Arbi Hillel Soudani.
Pjaca forms part of a five-man midfield, playing behind lone forward Junior Fernandes.
Olympiacos: Jimenez; Siovas, Masuaku, Botia, Fortounis; Milivojevic, Kasami, Elabdellaoui, Hernani, Seba, Ideye
Dinamo Zagreb: Eduardo; Matel, Goncalo, Taravel, Pivaric; Antolic, Machado, Rog, Hodzic, Pjaca; Fernandes
Subs: Jezina, Musa, Coric, Sovsic, Henriquez, Sigali, Pavicic
Following all the action from the Group F clash with Sports Mole's live text commentary.