Atletico Madrid are expected to be without leading scorer Diego Costa and key attacker Arda Turan for next weekend's Champions League final against Real Madrid.
Costa, who has been troubled with a thigh injury in recent months, limped out of Saturday's 1-1 draw with Barcelona at the Camp Nou after just 14 minutes.
The Brazilian-born Spanish international looked visibly distressed on the bench and according to Atletico president Enrique Cerezo, the striker will be out for "at least two weeks".
Turan, meanwhile, who entered the match with a pelvic injury, limped off in the 23rd minute following a clash with Cesc Fabregas.
Both players will undergo tests over the next 24 hours.