Real Madrid boss Carlo Ancelotti will shuffle his pack on Tuesday evening, as the reigning European champions take on Shakhtar Donetsk in the Champions League.
Los Blancos beat the Ukrainian giants 2-1 in Madrid last week before running out 1-0 winners over Getafe on Saturday, and Karim Benzema was left out of the La Liga contest.
Ancelotti said that the Frenchman was 'rested', but he missed Friday's training session with a slight muscular issue.
Benzema is expected to be back in the side here, but Thibaut Courtois's troublesome back injury will rule him out once again, with the Belgian instead returning against Barcelona in El Clasico next weekend.
Dani Ceballos is definitely out of the match with a hamstring issue, while Eder Militao is suffering with a muscular problem, which could see Antonio Rudiger start alongside David Alaba at the back despite the Brazilian being named in the squad.
Andriy Lunin will continue between the sticks with Courtois indeed ruled out, while Lucas Vazquez could be handed a start at right-back as part of the rotations.
Eduardo Camavinga is also in line for a spot in midfield, with Luka Modric, who played the full 90 minutes against Getafe, potentially being rested.
Federico Valverde could also drop down to the bench ahead of the Barcelona match, with Rodrygo and Vinicius Junior potentially joining Benzema in the final third of the field.
Real Madrid possible starting lineup: Lunin; Vazquez, Rudiger, Alaba, Mendy; Camavinga, Tchouameni, Kroos; Rodrygo, Benzema, Vinicius body check tags ::