Loanee midfielder Michael Essien has been handed a role at right-back for Real Madrid's trip to Borussia Dortmund.
The Ghana international will form part of a back four that also sees Sergio Ramos start at left-back.
Meanwhile, the hosting Germans will begin the encounter with Robert Lewandowski as a lone striker.
Dortmund: Weidenfeller; Piszczek, Subotic, Hummels, Schmelzer; Kehl, Bender; Gotze, Reus, Grosskreutz; Lewandowski
Madrid: Casillas; Ramos, Varane, Pepe, Essien; Khedira, Alonso; Di Maria, Ozil, Ronaldo; Benzema
