Real Madrid will resume their La Liga campaign away to Alaves on Saturday night, but there will be no Zinedine Zidane in the dugout as the Frenchman self-isolates following a positive coronavirus test.
Los Blancos followed a 2-1 defeat to Athletic Bilbao in the semi-finals of the Spanish Super Cup with a 2-1 loss to third-tier side Alcoyano in the Copa del Rey on Wednesday.
Madrid are on an eight-game unbeaten run in the league and currently sit second in the table, but the reigning champions are four points behind leaders Atletico Madrid, who have two games in hand.
Here, Sports Mole looks at how Zidane's side could line up this weekend.
Out: Rodrygo Goes (thigh), Dani Carvajal (knock), Sergio Ramos (knee), Nacho (coronavirus), Federico Valverde (muscle)
> Click here for Real Madrid's latest injury and suspension news ahead of this match
Madrid will again be without the services of Rodrygo Goes due to a thigh problem, while versatile defender Nacho will not be available following a coronavirus scare.
Dani Carvajal was suspended for the clash with Osasuna on January 9 before missing out against Athletic and Alcoyano through injury, and the Spaniard is also out of this game, meaning that Lucas Vazquez could get the nod at right-back.
Club captain Sergio Ramos has also failed to recover from the problem that forced him to miss out against Alcoyano, which could see Eder Militao continue in the middle of the defence alongside Raphael Varane.
There will be changes from the Copa del Rey clash, with Eden Hazard and Marco Asensio likely to join Karim Benzema as part of a front three, with Vinicius Junior expected to drop to the bench for Saturday's contest.
Casemiro should be joined by Toni Kroos and Luka Modric in midfield, meanwhile, with Federico Valverde absent due to a muscular problem.