Huesca vs. Villarreal (Saturday, 1.00pm)
Villarreal, who are currently fourth in the league, will expect to come away from this encounter with all three points, with hosts Huesca currently languishing at the foot of the table.
We say: Huesca 0-2 Villarreal
Villarreal will come into this tie determined to pick up the points they dropped at Granada last time out. As promising as Huesca have been this season, we think Pacheta's men will struggle against the might of this Villarreal side.
Our tipster partners are predicting a double chance bet on a home win or an away win.
Sevilla vs. Cadiz (Saturday, 3.15pm)
Sevilla come into this game knowing that a win could propel them all the way into third place, ahead of both Barcelona and Villarreal, while Cadiz will be looking to extend their La Liga unbeaten streak to five games.
We say: Sevilla 2-1 Cadiz
Lopetegui's Sevilla side are playing some fantastic football at the moment and look more than capable of outgunning Cadiz. However, expect a fightback from the Yellow Submarine because they rarely go down quietly.
Our tipster partners are predicting over 1.5 goals.
Real Sociedad vs. Real Betis (Saturday, 5.30pm)
Following a spate of defeats to their high-flying rivals, La Real have seen their Champions League dream slowly wither in recent weeks. Imanol Alguacil will hope a win against Betis could get their La Liga ambitions back on track.
We say: Real Sociedad 2-2 Real Betis
This game could be a real blockbuster, mainly because both sides have shaky defences and an extremely chaotic energy about them at the moment. We do not think anything will separate the two teams come the end of the game, but we recommend this one for the neutrals. Expect goals.
Our tipster partners are predicting under 3.5 goals.
Alaves vs. Real Madrid (Saturday, 8.00pm)
Los Blancos were dumped out of the Copa del Rey by third-tier side Alcoyano on Wednesday, but they are currently on an eight-game unbeaten run in La Liga, which has moved them into second spot in the table.
We say: Alaves 1-2 Real Madrid
The pressure is firmly on Zidane heading into this weekend's clash, and the Frenchman simply cannot afford another poor result. Alaves are capable of making it difficult for the champions despite their disappointing form, but we expect the visitors to claim all three points courtesy of a narrow success.
Our tipster partners are predicting an away win.