Los Blancos will now switch their attention back to the league, though, and anything other than a defeat against Sevilla would move them to the top of the table as Barcelona are not in action until Sunday night.
Here, Sports Mole looks at how the capital giants could line up at the Bernabeu.
Madrid will be without the services of in-form midfielder Federico Valverde, who picked up a red card during the Spanish Super Cup final against Atletico last weekend.
Marco Asensio and Eden Hazard also remain on the sidelines with knee and ankle injuries respectively, while Sergio Ramos, Karim Benzema, Gareth Bale and Luka Jovic are all doubts.
Ramos is expected to overcome an ankle problem to feature against his former club, though, while Bale should shake off an illness in time for Saturday's contest.
Jovic is seemingly more likely than Benzema to recover from his fitness concern, meanwhile, meaning that the Serbian, who has only scored once in 17 appearances since arriving from Eintracht Frankfurt, could be handed another chance to impress in the final third of the field.
Valverde's absence should see Luka Modric, Toni Kroos and Casemiro feature in midfield, and Isco is expected to be given the nod over Brazilian pair Vinicius Junior and Rodrygo Goes in the final third.