Aurelio Andreazzoli's first game in charge of Roma has brought sweeping changes for their Serie A clash against Sampdoria.

Maarten Stekelenburg returns in goal, while Daniele De Rossi starts in the centre of midfield.

Andreazzoli has adopted a 3-5-2 system, with Francesco Totti partnering Pablo Daniel Osvaldo up front and Erik Lamela out wide.

Pedro Obiang returns from suspension for Sampdoria, but Eder is missing due to family issues.

Angelo Palombo is also missing for Delio Rossi's side due to an injury.

Mauro Icardi, 19, leads the line and is expected to provide goals in today's tough encounter.

Sampdoria: Romero; De Silvestri, Gastaldello, Rossini, Costa; Poli, Obiang, Krsticic, Estigarribia; Soriano, Icardi

Roma: Stekelenburg; Marquinhos, Burdisso, Castan; Lamela, De Rossi, Pjanic, Bradley, Marquinho; Osvaldo, Totti