Sheff Utd vs. Bournemouth (Saturday, 12.45pm)
The Blades are currently sixth in the table and two points ahead of seventh-place Middlesbrough, while the Cherries are second and six points clear of third-place Huddersfield Town.
We say: Sheffield United 1-1 Bournemouth
Bournemouth will not want to get into a rut and start looking nervously over their shoulder, so we expect a response from Scott Parker's side here. But Sheffield United have been invincible at home under Paul Heckingbottom and have plenty to play for themselves, so we think this game will end level.
Blackburn vs. Blackpool (Saturday, 3.00pm)
Meanwhile, Blackpool have recently dropped down to 16th position on the back of two successive defeats, and Neil Critchley's side may relish a second North-West derby in succession.
We say: Blackburn Rovers 2-1 Blackpool
With both clubs showing very little form, this is a difficult match to call. It may come down to who wants it most and with Rovers desperately needing three points to build some momentum, we are backing a narrow home win.
Bristol City vs. Peterborough (Saturday, 3.00pm)
At a time when the visitors are 10 points adrift of safety with six matches remaining, Bristol City find themselves in 19th position in the standings after three matches without success.
We say: Bristol City 2-1 Peterborough United
With draws no longer good enough for Peterborough, we expect Posh to go on the attack at Ashton Gate. However, there has been little wrong with Bristol City's attacking play this campaign, and extra space could lead to a hard-fought success for the Robins.
Middlesbrough vs. Hull City (Saturday, 3.00pm)
Meanwhile, Hull make the trip to the Riverside Stadium looking for a maximum return which will realistically ensure that they are playing second-tier football next season.
We say: Middlesbrough 3-1 Hull City
With the pressure on Arveladze and his Hull squad to a certain degree, this does not represent a free hit as some may perceive it to be. That said, we still expect Boro to come through with another victory at the Riverside, potentially having to produce a strong closing half-hour to get over the line.
Millwall vs. Barnsley (Saturday, 3.00pm)
The Tykes now find themselves eight points adrift of safety with only seven games left to play, albeit with a game in hand over 21st-placed Reading, while the hosts have only recently dropped out of contention in the playoff race.
We say: Millwall 1-1 Barnsley
We see Barnsley coming out firing as they desperately look to keep their survival hopes alive, and they should cause the hosts plenty of issues.
The Den is never an easy place to visit, though, and we expect the Lions to have enough to, at least, force a share of the spoils against a team with arguably more to play for.
Nott'm Forest vs. Birmingham (Saturday, 3.00pm)
While Forest could potentially move into third position this weekend, Blues are looking to move closer to the 50-point mark now that their second-tier status has effectively been assured for another year.
We say: Nottingham Forest 2-0 Birmingham City
While Blues will be high in confidence after their recent form, a trip to the City Ground is currently the toughest test at this level. With that in mind, we expect another professional showing from Forest, who may score a goal in either half to make relatively light work of their opponents.
Preston vs. QPR (Saturday, 3.00pm)
The Hoops are currently five points adrift of the top six in ninth place, while the 13th-placed Lilywhites saw their own playoff ambitions wane a while ago.
We say: Preston North End 0-0 Queens Park Rangers
QPR are stuck in an almighty rut but against a Preston side with little to play for they may have more of a chance of getting a point or three. It is rare that the Lilywhites roll over for teams though, so we think this game will end level.
Reading vs. Cardiff (Saturday, 3.00pm)
Sitting 21st in the table, the Royals are currently eight points clear of the relegation zone, having played one game more than 22nd-place Barnsley. The Bluebirds sit 17th.
We say: Reading 2-0 Cardiff City
Reading are gradually building momentum and edging ever closer to safety, so we think they will get another important three points on the board at home. Cardiff have very little to play for and will be shaken by their derby defeat.
Swansea vs. Derby (Saturday, 3.00pm)
The Rams are currently 23rd in the table and nine points adrift of safety, while the Swans have very little to play for and sit 14th.
We say: Swansea City 2-1 Derby County
There is much more on the line for Derby but we cannot ignore the Rams' dreadful record away from home. Swansea are enjoying a good run of form and we think that the Welsh side will be victorious on this occasion.
West Brom vs. Stoke (Saturday, 3.00pm)
At a time when the Baggies still have faint hopes of an immediate return to the Premier League, Stoke are down in 15th position in the standings after a disappointing defeat at Reading earlier this week.
We say: West Bromwich Albion 2-1 Stoke City
While West Brom are currently in the habit of raising their game against the better teams, that has not been the case against the rest of the division. That said, Stoke have been disappointing on their travels for some time, and it would come as a surprise if the Baggies do not edge this contest.