Coventry, meanwhile, were amongst the relegation favourites prior to the start of the season but have battled their way to 18th, six points clear of the drop and are in good form ahead of this encounter.
Wednesday come into this contest in a desperate situation, sitting bottom of the Championship with just nine points after 19 games following their six-point deduction at the start of the season.
Furthermore, they are on a nine-game winless run in the league and have lost their last four in a row, slipping further and further from safety.
Two of the club's most serious on-field issues have been their goalscoring statistics and their disciplinary record.
Wednesday have scored just 10 goals in 19 games this term - the joint-worst in the league along with Derby County - and the Owls have had five players sent off in that time, at least two more than any other side.
Coventry will certainly hope to take advantage of Wednesday's struggles and maintain their own good recent form.
Having endured a difficult start to the season in which they lost seven of their opening 11 league games, the newly-promoted outfit have gone eight games unbeaten.
While five of those eight games were draws, it is a remarkable improvement from a side that looked certain to drop straight back down into League One.
Coventry have tightened up defensively in recent weeks, conceding just four times in their unbeaten run and keeping four clean sheets, a tally that manager Mark Robins will expect to be boosted against a profligate Wednesday outfit.
Sheffield Wednesday Championship form: DDLLLL
Coventry City Championship form: DDWDWD
Wednesday boss Pulis has a number of senior players absent due to injury ahead of Coventry's trip to Sheffield.
Dominic Iorfa, however, has been ruled out for the rest of the season with an Achilles tendon injury.
Coventry head coach Robins also has several players unavailable for this contest.
Sheffield Wednesday possible starting lineup:
Wildsmith; Odubajo, Lees, Dunkley, Van Aken, Reach; Harris, Pelupessy, Shaw, Bannan; Windass
Coventry City possible starting lineup:
Wilson; Ostigard, McFadzean, Hyam; Dabo, Hamer, Sheaf, McCallum; O'Hare, Allen; Walker
We say: Sheffield Wednesday 0-1 Coventry City
Wednesday's poor form and struggles in front of goal should see a Coventry side unbeaten in eight and boasting a strong recent defensive record come away with all three points - and possibly a clean sheet - on Saturday.