Premier League trio Fernando Torres, David Silva and Juan Mata have all been named in Spain's 23-man squad for Euro 2012.
There is no spot for Manchester United goalkeeper David de Gea, while Alvaro Negredo has been selected in place of the injured David Villa.
Cesc Fabregas has also been called up by manager Vicente Del Bosque, despite recently picking up a minor hamstring injury.
Midfielders Xavi Hernandez, Andres Iniesta and Xabi Alonso are also in the squad for the tournament in Poland and Ukraine.
Holders Spain begin their campaign against Italy on Sunday, June 10.
Spain squad for Euro 2012:
Goalkeepers:
Iker Casillas (Real Madrid), Pepe Reina (Liverpool), Victor Valdes (Barcelona)
Defenders:
Alvaro Arbeloa (Real Madrid), Sergio Ramos (Real Madrid), Juanfran (Atletico Madrid), Jordi Alba (Valencia), Raul Albiol (Real Madrid), Gerard Pique (Barcelona), Javi Martinez (Athletic Bilbao)
Midfielders:
Xavi Hernandez (Barcelona), Sergio Busquets (Barcelona), Andres Iniesta (Barcelona), Xabi Alonso (Real Madrid), David Silva (Manchester City), Santi Cazorla (Malaga), Cesc Fabregas (Barcelona), Juan Mata (Chelsea)
Strikers:
Jesus Navas (Sevilla), Pedro (Barcelona), Fernando Llorente (Athletic Bilbao), Fernando Torres (Chelsea), Alvaro Negredo (Sevilla)