Tottenham Hotspur will be looking to book their spot in the fifth round of the FA Cup when they travel to fellow Premier League club Southampton on Saturday afternoon.

Spurs needed a replay to overcome Middlesbrough in the third round, while their form in the last few weeks has been inconsistent.

Jose Mourinho's side will enter this match off the back of an important win, however, having recorded a 2-1 victory over Norwich City in the Premier League on Wednesday night.

Here, Sports Mole rounds up Tottenham's injury and suspension news ahead of the FA Cup clash.

Harry Kane

Status: Out
Type of injury: Hamstring
Possible return date: Unknown

Harry Kane is expected to be on the sidelines until at least April following hamstring surgery. However, there have been suggestions that the England captain faces a battle to return before the end of the season.

Moussa Sissoko

Status: Out
Type of injury: Knee
Possible return date: Unknown

Moussa Sissoko has been absent since picking up a knee injury during the Premier League clash with Southampton on New Year's Day. The Frenchman has since undergone surgery and is now facing the next few months on the sidelines.

Ben Davies

Status: Out
Type of injury: Ankle
Possible return date: Unknown

Ben Davies has been on the sidelines since the end of November due to ankle injury. The Welshman has recently been in Qatar receiving treatment, and it remains unclear when he might return.

Harry Winks

Status: Out
Type of injury: Ankle
Possible return date: Unknown

Harry Winks will not be available this weekend having picked up an ankle injury against Norwich on Wednesday night. The England international is now facing a period on the sidelines, although Tottenham, as it stands, have neither confirmed a timeframe nor revealed the full extent of the problem.

Danny Rose

Status: Major doubt
Type of injury: Back
Possible return date: January 25 (vs. Southampton)

Danny Rose, who continues to be linked with a move away from Tottenham, has not been in involved in any of Mourinho's last three squads. The Spurs boss recently revealed that the defender was carrying a slight back issue, although he could potentially return for Saturday's clash with the Saints.

TOTTENHAM HOTSPUR'S SUSPENSION LIST

Tottenham have no suspensions concerns heading into the FA Cup fixture.