Emmanuel Adebayor and Roberto Soldado have been chosen to start up front for Tottenham Hotspur's clash against Southampton this afternoon.
The forwards will be supported by Erik Lamela and Gylfi Sigurdsson, who start out wide.
Christian Eriksen and Moussa Dembele will be deployed in central midfield as interim manager Tim Sherwood goes for a traditional 4-4-2 formation.
Meanwhile, Southampton have made three changes to their side, with Adam Lallana, Danny Fox and Morgan Schneiderlin starting this afternoon.
Jay Rodriguez and Rickie Lambert lead the line for Mauricio Pochettino's side.
Southampton: Gazzaniga, Chambers, Lovren, Hooiveld, Fox, Cork, Schneiderlin, Davis, Lallana, Rodriguez, Lambert
Tottenham: Lloris, Walker, Dawson, Chriches, Rose, Lamela, Dembele, Eriksen, Sigurdsson, Adebayor, Soldado
You can follow our live minute-by-minute commentary of today's game here.
