Southampton have made one change from their 8-0 demolition of Sunderland last week, with Senegal midfielder Sadio Mane replacing Shane Long for this afternoon's Premier League clash at home to Stoke City.
Potters manager Mark Hughes, meanwhile, has changed two players in the starting XI from the team which beat Swansea City last week.
American Geoff Cameron makes his first league start of the season, with Jonathan Walters also coming in, while Victor Moses has shaken off a knock in time to start at St Mary's.
All four previous Premier League meetings between the two teams have ended in a draw.
Southampton: Forster, Clyne, Fonte, Alderweireld, Bertrand, Cork, Schneiderlin, S Davis, Mane, Tadic, Pelle
Subs: K Davis, Yoshida, Gardos, Long, Wanyama, Mayuka, Reed
Stoke City: Begovic, Bardsley, Shawcross, Wilson, Pieters, Cameron, Nzonzi, Walters, Adam, Moses, Crouch
Subs: Sorensen, Huth, Arnautovic, Diouf, Sidwell, Assaidi, Krkic
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