Gareth Bale will go up against his former Tottenham Hotspur teammate Luka Modric when Wales take to the field in Swansea against Croatia.
Wales manager Chris Coleman has been forced to make changes to his side that defeated Scotland due to the suspension of midfielder Aaron Ramsey.
Jack Collison has also been forced to withdraw through injury, while Andy King has been slotted in midfield due to the nation's injury crisis.
Meanwhile, Craig Bellamy keeps his place up front.
Wales: Myhill; Gunter, B.Davies, Collins, A.Williams; King, J.Williams, Ledley, Robson-Kanu; Bellamy, Bale
Croatia: Pletikosa; Srna, Corluka, Lovren, Strinic; Rakitic, Modric, Sammir, Badelj; Mandzukic, Eduardo