The Hornets are currently 17th in the table, just three points outside of the relegation zone, while Brentford occupy 13th position, four points above their opponents in this match.
All things considered, Brentford will be delighted with their 2021-22 Premier League campaign to date, winning four, drawing five and losing six of their 15 matches to collect 17 points, which has left them in 13th spot.
The Bees are seven points clear of the relegation zone heading into Friday's contest, and another victory would be a huge step in the right direction, as they bid to stay clear of the bottom three this term.
Thomas Frank's side have only lost one of their last four in the Premier League, while they picked up a welcome point away to Leeds United last weekend, with Shandon Baptiste and Sergi Canos netting in a 2-2 draw.
Brentford have actually performed better on their travels than at home this season, with 10 of their 17 points coming away from home, while only Burnley (six) and Norwich City (five) have picked up fewer home points than the Bees during the 2021-22 Premier League season.
Frank's team did beat Watford 2-0 at home in the corresponding match during the 2020-21 Championship campaign, but that was their first victory against the Hornets of any kind since April 1977.
Watford were so impressive against Manchester United on November 20, running out 4-1 winners over the Red Devils, but they have not been able to build on the result against the 20-time English champions.
Indeed, Claudio Ranieri's side will enter this match off the back of three straight defeats, suffering a 4-2 reverse to Leicester City on November 28 before losing their next two home matches against Chelsea and Manchester City.
The Hornets have actually lost more games (10) than any other team in the Premier League this season, but they are just outside of the relegation zone, collecting 13 points from their 15 matches.
Ranieri's team are just three points ahead of basement side Norwich City, though, and their next two games, away to Brentford and away to Burnley, are huge in the context of their season.
Friday's clash at the Brentford Community Stadium will be the first ever Premier League meeting between these two teams, while it will be just their fifth contest of any kind since January 1998.
Brentford will again be without the services of Mathias Jorgensen, Kristoffer Ajer, David Raya, Tariqe Fosu-Henry and Josh Dasilva through injury, while Canos will miss the contest through suspension.
Frank could otherwise name the same side that started against Leeds last time out, with Baptiste again potentially getting the nod in midfield ahead of Frank Onyeka.
Brentford possible starting lineup:
Fernandez; Goode, Jansson, Pinnock; Rasmussen, Baptiste, Norgaard, Janelt, Henry; Mbuemo, Wissa
Watford possible starting lineup:
Bachmann; Femenia, Troost-Ekong, Cathcart, Rose; Dennis, Cleverley, Kucka, Sissoko, Pedro; King
We say: Brentford 2-2 Watford
There should be goals in this contest, with both sides likely to view this match as the ideal chance to put three points on the board. The two teams will again be missing a number of players through injury, and neither defence is particularly secure, so an entertaining 2-2 draw could be on the cards.
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