Meanwhile, Blues make the short trip to The Hawthorns having failed to win any of their last five matches at the second tier, leaving the club in 16th position in the standings.
At one stage earlier this year, it appeared that West Brom would canter to promotion to the Premier League, especially with Leeds United enduring a slump which threatened to remove them from a top-two spot.
However, picking up just one point from games against Wigan Athletic and Swansea City, coupled with Leeds putting together an unforeseen resurgence, has left the Baggies in second place and looking over their shoulder.
Although there is still a six-point gap to third-placed Fulham, Slaven Bilic will be aware that his team must get back on track as soon as possible having also gone two games without troubling the scoresheet.
Brentford also lie in wait for West Brom on Tuesday night, placing more emphasis on the club to maintain their 10-point gap over the Bees ahead of their upcoming meeting at Griffin Park.
As far as Birmingham are concerned, Pep Clotet will only have consolidation on his mind after the club's five-game streak without a victory.
While four draws have come during that period, the 3-1 defeat at home to Reading last weekend has left Blues just eight points above the relegation zone.
Two victories from their remaining nine games should be enough to starve off the threat of a drop down to League One, but Clotet will not want to see their previous hard word undone by an uninspiring end to the campaign.
Despite Clotet's focus potentially being on crucial home fixtures against Hull City and Huddersfield Town over the next week, the Spaniard knows that avoiding defeat at their biggest rivals in the division will get the club's supporters back on side ahead of that double-header.
West Bromwich Albion Championship form: WDWWLD
West Bromwich Albion form (all competitions): DWWLLD
Birmingham City form: WDDDDL
Birmingham City (all competitions): DDDDLL
Bilic must also decide whether to hand a rest to Hal Robson-Kanu, who is likely to be the preferred option in attack against Brentford on Tuesday.
After witnessing his team's capitulation against Reading, Clotet will inevitably make alterations to his Birmingham starting lineup.
Jude Bellingham may be one of the players to drop to the substitutes' bench after a week which has seen him hold discussions with Manchester United.
West Bromwich Albion possible starting lineup:
Johnstone; O'Shea, Ajayi, Bartley, Townsend; Sawyers, Livermore, Krovinovic; Pereira, Austin, Grosicki
Birmingham City possible starting lineup:
Camp; Colin, Roberts, Clarke-Salter, Pedersen; Crowley, Sunjic, Gardner, Mrabti; Jutkiewicz, Hogan
We say: West Bromwich Albion 3-1 Birmingham City
Although the Baggies have failed to win their last two Championship matches without scoring a goal, we feel that the promotion contenders will return to form against opposition who have lost the momentum they had generated at the start of the year.
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