West Brom are currently 19th in the table, 11 points behind 17th-placed Newcastle United, while Brighton are 16th in England's top flight, just four points clear of the relegation zone.
West Brom's situation in the Premier League is not quite terminal, but it would be fair to say that a huge turnaround would have to take place for the Baggies to escape the relegation zone.
Indeed, a record of two wins, eight draws and 15 defeats from 25 matches has left them in 19th position in the table, 11 points behind 17th-placed Newcastle on the same number of matches, while they are also eight points from 18th-placed Fulham, who are now threatening to pull themselves out of the drop zone.
Sam Allardyce's side are without a victory in the league since the middle of January, though, and have won just twice in England's top flight all season, which is an indication of just how much they have struggled.
A win over Brighton would certainly boost their chances of survival, and they recorded a 2-0 victory over the Seagulls when the two teams last met at the Hawthorns in the Premier League in January 2018.
Brighton have impressed many with their football this season, but there is no question that Graham Potter's side are in a relegation battle as they sit just four points clear of 18th-placed Fulham on the same number of games.
The Seagulls have lost just nine of their 25 league matches this term, which is far from disastrous, but too many draws (11) have prevented them from pushing higher up the table.
Potter's team recorded back-to-back wins over Tottenham Hotspur and Liverpool on January 31 and February 3 respectively, but they have picked up just two points from their three games since and suffered a surprise 2-1 home defeat to Crystal Palace on Monday night.
The two teams appeared to be sharing the points at the Amex Stadium, but Christian Benteke's 95th-minute winner secured a huge three points for Palace and left Brighton looking over their shoulders.
The Seagulls have been relatively solid on their travels this term, picking up 16 points from 12 matches, and they will be taking on a West Brom side with the worst home record in this season's Premier League.
West Bromwich Albion Premier League form: LDLLDD
Brighton & Hove Albion Premier League form: DWWDDL
Brighton & Hove Albion form (all competitions): WWDLDL
West Bromwich Albion possible starting lineup:
Johnstone; Furlong, O'Shea, Bartley, Townsend; Pereira, Maitland-Niles, Yokuslu, Gallagher, Phillips; Diagne
Brighton & Hove Albion possible starting lineup:
Sanchez; Veltman, White, Dunk, Burn; Alzate, Bissouma, Gross; Mac Allister; Maupay, Trossard
We say: West Bromwich Albion 0-0 Brighton & Hove Albion
Both sides desperately need the three points, but we are struggling to separate them in this match. The pair shared the points at the Amex earlier this season, while they have 19 league draws between them in 2020-21. A goalless draw would not be welcomed by either manager, but we are backing the stalemate here.
Watch the Sports Mole Football Shorts prediction for this game below: