Both clubs have collected two wins from four matches, with the visitors in a position where they will move joint-top with victory at the New Malatya Stadium.
Fatih Karagumruk have been one of the stories of Turkish football over the past few years, earning back-to-back promotions and claiming eighth position on their return to the top flight.
Naturally, suggestions have been made over whether they have reached their ceiling, but claiming seven points from a possible 12 have put Francesco Farioli's side in a favourable spot.
While caution is required with each of those points coming against teams currently featuring in the bottom seven, the Black Red thrashed Adana Demirspor by a 4-0 scoreline in their first game after the international break.
Karagumruk also impressed in losing just 1-0 at unbeaten leaders Besiktas, and there is genuine optimism that they can qualify for the Europa League or Europa Conference League.
The defence deserve credit for conceding just three goals, but Aleksandar Pesic has caught the eye at the other end of the pitch with three strikes of his own.
Malatyaspor will also be delighted with their start to the campaign, their two defeats coming against early pacesetters Besiktas and Trabzonspor.
Even though they were comfortably beaten by both teams, Irfan Buz will instead focus on the victories achieved against Goztepe SK and Gaziantep FK.
Clean sheets were kept during both fixtures, a considerable show of character after shipping five goals on the opening day of the season.
While Fabio Borini is making progress towards a return, the Italian is again expected to miss out here due to a lack of fitness.
Farioli may stick with the team which breezed past Demirspor last time out.
Yeni Malatyaspor possible starting lineup:
Damlu; Wallace, Kaya, Ciftpinar; Eskilhellac, Nshimirimana, Ndong, Aabid, Haddadi; Buyuk, Kanatsizkus
Fatih Karagumruk possible starting lineup:
Viviano; Hedenstad, Luckassen, Zukanovic, Erkin; Oztumer, Biglia, Bertolacci; Torun, Pesic, Frei
We say: Yeni Malatyaspor 2-2 Fatih Karagumruk
With both teams having the freedom to push for all three points, we expect an entertaining encounter on Friday night.
However, these sides could cancel each other out, eventually having to settle for a share of the spoils.
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