Gloucester Rugby can do the double over London Irish in the Amlin Challenge Cup on Saturday when the two teams go head to head at Kingsholm Stadium.
The West Country side kept up their 100% record in Pool 1 last weekend as they ran out 29-22 winners at the Madejski Stadium.
However, London Irish come into the match just two points behind in the standings.
The hosts have made a number of changes to their starting lineup, with Jimmy Cowan, Akapusi Qera and Billy Twelvetrees all selected by coach Nigel Davies.
Dan Murphy, Rupert Harden, Will James, Ben Morgan and Rob Cook are also given places in the team.
Shane Geraghty, Guy Armitage, Kieron Low and James Sandford will all start for the visitors.
Recent form:
Gloucester: LLWWLW
London Irish: LWLLLL
Lineups:
Gloucester: Cook, Sharples, Tindall, Twelvetrees, Monahan, Burns, CowaN, Murphy, Dawidiuk, Harden, James, Hamilton, Savage, Qera, Morgan
Replacements: Britton, Wood, Knight, Kalamafoni, Cox, Robson, Molenaar, Thomas
London Irish: Homer, Ojo, Joseph, Armitage, Watson, Geraghty, Allinson, Lahiff, Paice, Aulika, Sandford, Evans, Low, Gibson, Hala'ufia
Replacements: Lawson, Yanuyanutawa, Halavatau, Garvey, Danaher, Tagicakibau, Shingler, Moates
Sports Mole says: Gloucester to bag the points