England midfielder Alli is suffering from a hamstring injury and will miss out.
Arsenal will be without striker Eddie Nketiah.
The England Under-21 international was sent off in Tuesday's 1-1 draw with Leicester and will miss the next three games after an appeal against the decision was unsuccessful.
Tottenham provisional squad: Lloris, Vorm, Gazzaniga, Aurier, Sanchez, Alderweireld, Vertonghen, Cirkin, Davies, Sessegnon, Winks, Lo Celso, Ndombele, Sissoko, Fernandes, Skipp, Moura, Lamela, Son, Kane, Bergwijn.
Provisional Arsenal squad: Martinez, Macey, Bellerin, Soares, Sokratis, Luiz, Holding, Mustafi, Kolasinac, Tierney, Xhaka, Guendouzi, Torreira, Ceballos, Maitland-Niles, Willock, Ozil, Nelson, Pepe, Aubameyang, Lacazette.