Jackson Martinez's 15th-minute strike has given Porto the half-time lead against Atletico Madrid at Estadio do Dragao this evening.
The Colombian forward stooped low to head home after getting the better of Atleti defender Diego Godin.
Raul Garcia let fly with a long-range effort that went narrowly over Helton's crossbar on the half-hour mark for the visitors, but Atleti's best chance came two minutes later.
Juanfran beat the offside trap from Tiago's through-ball but his cross for Arda Turan went to waste as the Turk was off-balance when he took the shot.