Bayer Leverkusen make the trip to Benfica in the Champions League on Tuesday with a first-place finish in Group C within their grasp.
The Germans, who are already assured a spot in the last 16, currently have a one-point lead over Monaco in the standings and will go through as group leaders with a win.
A draw could also be enough for the Bundesliga outfit should Monaco fail to beat Zenit St Petersburg in their final game. Meanwhile, Benfica are destined to finish at the bottom of the table following three defeats in their first five games.
Leverkusen saw off the Portuguese side 3-1 when they met at the BayArena two months ago as goals from Stefan Kiessling, Son Heung-min and Hakan Calhanoglu did the damage.
Luisao and Andreas Samaris are both suspended for the home side, while Eliseu and Silvio are both missing through injury. Kyriakos Papadopoulos and Stefan Reinartz are sidelined for the visitors.
Benfica:
Form in Champions League: LLDWL
Form in all competitions: WWWLWW
Possible starting lineup: Julio Cesar; Maxi Pereira, Benito, Jardel, Andre Almeida; Perez, Gaitan, Talisca; Gaitan, Salvio, Lima
Bayer Leverkusen:
Form in Champions League: WLWWWL
Form in all competitions: WDWLWL
Possible starting lineup: Leno; Donati, Toprak, Spahic, Wendell; Bellarabi, Bender, Castro, Son; Calhanoglu, Kiessling
Sports Mole says: 0-2