Huddersfield vs. Birmingham (Wednesday, 7.45pm)
At a time when the Terriers are in sixth position, Blues are down in 19th place after losing five of their last six fixtures.
We say: Huddersfield Town 2-1 Birmingham City
Swansea vs. West Brom (Wednesday, 7.45pm)
On the other hand, the hosts shall be hoping to push away from the relegation zone and start climbing the table after a mixed start to the season.
We say: Swansea City 1-2 West Bromwich Albion
Both teams head into this particular fixture with lots of confidence because of their recent results, and that should lead to a closely-contested match.
However, the visitors have only lost once this season and that is unlikely to change this weekend, even though Swansea will push them.
Middlesbrough vs. Barnsley (Wednesday, 7.45pm)
Meanwhile, the Tykes travel to the North-East on the back of four successive defeats, leaving Markus Schopp under increasing pressure in the dugout.
We say: Middlesbrough 1-1 Barnsley
Fulham vs. Cardiff (Wednesday, 7.45pm)
While the Cottagers now sit in third place in the Championship standings, Cardiff are down in 20th position after six successive defeats.
We say: Fulham 3-0 Cardiff City
Preston vs. Coventry (Wednesday, 7.45pm)
Two teams at opposite ends of the Championship will collide on Wednesday when Coventry City make the trip to Deepdale Stadium, where a victory could put them into second place.
Preston North End have not had as much success so far this season, and they will be hoping to get back on track as the Lilywhites have not won in the league across their last seven matches.
We say: Preston North End 0-2 Coventry City
Preston North End have been picking up a lot of draws lately, but this is going to be a tough fixture for them to take anything from due to the confidence of the visitors.
Coventry have the possibility of going into second place in midweek and it is unlikely that they will be letting that slide.
Hull City vs. Peterborough (Wednesday, 7.45pm)
The hosts are only a single point away from that themselves, meaning a victory for the visitors would drag the Tigers into it, making this a crucial fixture for both clubs.
We say: Hull City 2-2 Peterborough United
This game is crucial for both teams, but it is also one that neither will want to lose and because of that it could end up being one that is played very cautiously.
That is why they could end up sharing the spoils with a draw, in a match that is likely to feature some goals due to the poor defensive record of each squad.
Reading vs. Blackpool (Wednesday, 8.00pm)
The hosts have the opportunity to extend their run of victories to three consecutive games, which would potentially put them in the playoff positions.
We say: Reading 2-1 Blackpool
While Reading are the favourite team in this particular fixture, Blackpool will be keen to return to winning ways and get themselves back on track in midweek.
The fixture is sure to be a closely contested one as both teams are in strong form as of late with great attacking options, but the hosts should have enough experience to see them through.