After Juventus secured their seventh successive qualification for the Champions League knockout stages with a late 2-1 victory over Ferencvaros last week, Andre Pirlo may be tempted into heavily rotating his side against Dynamo Kiev on Wednesday.
The Italian champions are relying on Barcelona stumbling against Hungarian side Ferencvaros in the other match in the group to have a realistic chance of finishing ahead of them in Group G, having lost 2-0 at home to Ronald Koeman's side earlier in the campaign.
With Juventus six points behind Serie A leaders Sassuolo after a disappointing 1-1 draw at Benevento on Saturday, the league may now take full priority for Pirlo until the knockout stages begin.
Here, Sports Mole looks at how Juventus could line up for Wednesday's showdown against Mircea Lucescu's side.
Out: Giorgio Chiellini (muscular), Merih Demiral (muscular), Stefano Gori (shoulder)
Doubtful: Cristiano Ronaldo (ankle)
With Giorgio Chiellini and Merih Demiral ruled out due to muscle injuries, Pirlo's ability to rotate his defence is compromised. Danilo and Juan Cuadrado are likely to continue in their unfamiliar centre-back and right-back roles in order to gain more experience, with Leonardo Bonucci and Gianluca Frabotta joining them.
Legendary goalkeeper Gianluigi Buffon could be called upon to play in his 124th Champions League match between the sticks, taking him level with former Manchester United midfielder Paul Scholes into the top 10 of the record appearance holders in Europe's elite competition.
In midfield, Arthur and Adrien Rabiot should receive a rest. with Weston McKennie and Rodrigo Bentancur likely to replace them. Federico Chiesa, Dejan Kulusevski and Federico Bernadeschi could support Alvaro Morata after the Spaniard's sending off against Benevento rules him out of Saturday's Turin derby against Torino.
The Champions League's all-time record goalscorer Cristiano Ronaldo suffered an ankle injury earlier in the month and is likely to be rested once more, with Paolo Dybala also potentially spared for the weekend.
