Spezia Calcio vs. Sassuolo (Sunday, 11.30am)
Spezia Calcio kick off the first Serie A season in the club's history by hosting Sassuolo, and will be eager to make a good impression in the top flight.
Sassuolo, meanwhile, have already played their first league game, drawing 1-1 with Cagliari, and will hope to improve on that result as they build on last season's eighth-placed finish.
We say: Spezia Calcio 0-2 Sassuolo
Sassuolo have proven themselves a good outfit recently and should have little trouble claiming all three points from Serie A debutants Spezia.
Our tipster partners are predicting under 3.5 goals.
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Napoli vs. Genoa (Sunday, 2.00pm)
Napoli are looking to put a disappointing league season behind them will be keen to make it two wins out of two on Sunday, having already started their Serie A campaign with a 2-0 win over Parma.
However, their opponents Genoa beat Crotone 4-1 in their opening game and sit at the top of the fledgling league table. Genoa narrowly avoided relegation last season and will hope to survive more comfortably this term.
We say: Napoli 2-1 Genoa
Genoa may put up more resistance than their league position last season suggests they might, but Napoli have plenty of quality and should come out on top.
Our tipster partners are predicting a home win.
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Hellas Verona vs. Udinese (Sunday, 2.00pm)
Hellas Verona held a strong Roma side to a goalless draw in their first Serie A game of the season and now play host to Udinese.
Udinese - who finished 13th last season - are among the teams who have yet to play their first league fixture and will be hoping for a positive start.
We say: Hellas Verona 0-0 Udinese
Both sides have shown a propensity to play cautiously and both recorded poor attacking numbers last season. This one could be goalless.
Our tipster partners are predicting over 1.5 goals.
> Click here to read our full preview for this match
Crotone vs. AC Milan (Sunday, 5.00pm)
AC Milan make the trip to Crotone on Sunday afternoon looking to build on their opening-game victory over Bologna.
Meanwhile, Crotone are playing their first home fixture in Serie A since 2018 after earning promotion from the second tier.
We say: Crotone 1-4 AC Milan
Given the size of their defeat last weekend, this is not the ideal second fixture for the newcomers. Although Milan were far from convincing in the Europa League, we expect the visitors to cruise to victory at the weekend.
Our tipster partners are predicting under 3.5 goals.
> Click here to read our full preview for this match
Roma vs. Juventus (Sunday, 7.45pm)
Juventus will be looking to make it back-to-back victories at the start of their 2020-21 Serie A campaign when they travel to the Italian capital to face Roma on Sunday night.
The Old Lady started their title defence with a comfortable 3-0 success at home to Sampdoria last weekend, but Roma were on the wrong end of a 3-0 scoreline away to Hellas Verona.
We say: Roma 1-2 Juventus
Roma will be determined to bounce back from their disappointing start to the season, but it is difficult to look past Juve on this occasion. Kulusevski was excellent on his debut against Sampdoria, and we fancy the 20-year-old to play another leading role in a narrow success for the reigning champions.
Our tipster partners are predicting under 3.5 goals.
