Udinese vs. AC Milan (Sunday, 11.30am)
Serie A leaders AC Milan travel to Stadio Friuli on Sunday to take on struggling Udinese as they look to continue their unbeaten start to the campaign.
Records are already beginning to tumble as the Zlatan Ibrahimovic-inspired Rossoneri seemingly cruise over every hurdle set both at home and abroad.
Luca Gotti's Zebrette, meanwhile, have sunk to one of the worst starts in their history.
We say: Udinese 0-2 AC Milan
Udinese certainly have their work cut out to deny marauding Milan the points in the early Sunday kickoff, as their season has been a virtual write-off so far.
Even if the 'King' does not bag another brace, Saelemakers, Rafael Leao, Hakan Calhanoglu and co have more than enough guile and drive to put limited opposition to the sword.
Our tipster partners are predicting under 3.5 goals.
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Spezia vs. Juventus (Sunday, 2.00pm)
The battle of the Bianconeri takes place at Cesena's Stadio Dino Manuzzi on Sunday afternoon as Spezia welcome champions Juventus to their temporary home.
In a Serie A bout of flyweight versus heavyweight proportions, their kit colours are perhaps the only thing these contrasting clubs have in common.
We say: Spezia 1-2 Juventus
A true clash of cultures will play out on the unloved plastic pitch at Stadio Dino Manuzzi, as the home side bid manfully to resist the might of Juventus and their returning superstar Ronaldo.
Despite their relative attacking woes - and telling lack of a ruthless edge in recent times - we're backing the perennial champions to take care of business this time, with the increasingly essential Kulusevski again to the fore.
Our tipster partners are predicting an away win.
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Torino vs. Lazio (Sunday, 2.00pm)
Torino are set to welcome Lazio on Sunday as they continue to search for their first league win of the season, having picked up a 3-3 draw against free-scoring Sassuolo last Friday.
Meanwhile, Lazio will be hoping to get their season back on track following a miserable start to the 2020-21 campaign, despite a recent 2-1 win against Bologna.
We say: Torino 1-2 Lazio
Usually, Lazio would be able to conjure up a convincing win against Torino, especially as Giampaolo's men currently find themselves in the relegation zone. However, with a set of key players likely to miss the game and the Biancocelesti struggling this season, this may be a close encounter between the two teams.
Our tipster partners are predicting under 3.5 goals.
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Roma vs. Fiorentina (Sunday, 5.00pm)
Following a breathless 3-3 draw with leaders AC Milan, Roma and Beppe Iachini's Fiorentina sit side by side in the early Serie A table, as they meet at Stadio Olimpico on Sunday evening.
While Paulo Fonseca's team have recorded successive draws, the visitors arrive in the capital buoyed by back-to-back wins - in league and cup - during the past week.
We say: Roma 1-1 Fiorentina
The home side are already under pressure to close the gap on their top-four rivals, particularly with the scudetto race looking so open this year.
Fiorentina, then, can continue their recent run of positive results by stealing a point away from the capital - with Castrovilli, Ribery and fast-improving Callejon set to shine.
Our tipster partners are predicting under 3.5 goals.
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Napoli vs. Sassuolo (Sunday, 5.00pm)
Two of the top three clash at Stadio San Paolo on Sunday as the momentum building behind Napoli's 2020-21 Serie A campaign is set to be fiercely challenged by Roberto De Zerbi's competitive Sassuolo side.
Both teams sit on 11 points, just behind leaders AC Milan, and have so far been scoring at a prodigious rate.
We say: Napoli 2-1 Sassuolo
Club legend Diego Maradona turned 60 last week and declared he would like to see Napoli win the scudetto as a birthday present. That's a lot to ask, but the Partenopei can at least seal victory over one of their closest rivals in the form table.
Both sides' records suggest a flurry of late goals and an entertaining encounter, which Napoli can edge by virtue of their numerous options in attack.
Our tipster partners are predicting over 2.5 goals.
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Sampdoria vs. Genoa (Sunday, 7.45pm)
Sampdoria host local rivals Genoa on Sunday hoping to continue their superb run in the league after claiming back-to-back wins against Atalanta and Lazio.
However, Genoa will be wishing to bounce back from their recent league defeat against Inter Milan, losing 2-0 to the Nerazzurri.
We say: Sampdoria 2-1 Genoa
Sampdoria have been particularly dangerous going forward in recent times, so expect them to score a few goals against Genoa at the weekend. However, the visitors will be up for a derby - and now the majority of their key players have returned, we expect this to be a close encounter between the two teams.
Our tipster partners are predicting a double chance bet on a home win or an away win.