Andreas Ivanschitz has been recalled to the Mainz 05 starting lineup having only been on the bench last weekend.
Ivanschitz's selection means that there is no place in the XI for Niki Zimling, who has to settle for a place on the bench.
For Hamburg, nine-goal Korean striker Son Heung-Mincontinues up front with Rafael van der Vaart in behind him to create from midfield.
Mainz: Wetklo; Pospech, Svensson, Noveski, Diaz; Soto, Baumgartlinger; Muller, Ivanschitz, Risse; Szalai
Hamburg: Adler; Diekmeier, Mancienne, Westermann, Jansen; Badelj, Arslan; Skjelbred, Jiracek, Van der Vaart; Son