Manchester City continue the defence of their EFL Cup crown with a fourth-round tie versus Southampton on Tuesday evening.

A much-changed City side got the better of Preston North End in the last 32, leaving the club three rounds away from another appearance in the final.

Pep Guardiola's side head into the match having put together a three-match winning streak in all competitions, the latest of which came against Aston Villa on Saturday afternoon.

Here, Sports Mole predicts how City may line up for the encounter with the Saints.

Out: Leroy Sane (knee), Aymeric Laporte (knee), Rodri (hamstring), Oleksandr Zinchenko (knee), Fernandinho (suspended)

While Guardiola is expected to ring the changes for this contest, the likes of Kyle Walker, Nicolas Otamendi, Riyad Mahrez and Sergio Aguero are likely starters having been named on the substitutes' bench at the weekend.

Having been withdrawn during the second half against Villa, Raheem Sterling could also be handed a role in the team on Tuesday night.

Phil Foden could partner Ilkay Gundogan in midfield, with prospect Adrian Bernabe being provided with an opportunity in front of the duo.

Angelino should feature at left-back, while Eric Garcia is expected to partner Otamendi in the centre of the backline given that Fernandinho is serving a one-match ban.

Claudio Bravo will be handed a rare appearance between the sticks, with Ederson being rested for this contest.