Michel Vorm has been picked ahead of Hugo Lloris in goal for Tottenham Hotspur's FA Cup semi-final meeting with Manchester United at Wembley Stadium.
The Dutch custodian has been playing in his side's cup games this term and Mauricio Pochettino has kept faith in the club's second-choice stopper against the Red Devils.
Pochettino has made six changes in total from the XI that drew 1-1 against Brighton & Hove Albion, with Kieran Trippier, Davinson Sanchez, Eric Dier, Mousa Dembele and Dele Alli also drafted back in for Spurs.
United, meanwhile, have made five alterations to his side from Wednesday's 2-0 win at Bournemouth.
Alexis Sanchez, Romelu Lukaku, Ashley Young, Antonio Valencia and Nemanja Matic all come back into the starting XI, while Luke Shaw has been dropped from the squad.
Manchester United: De Gea; Valencia, Jones, Smalling, Young; Matic, Herrera, Pogba; Lingard, Lukaku, Sanchez
Subs: Pereira, Darmian, Lindelof, Fellaini, Mata, Martial, Rashford
Tottenham Hotspur: Vorm; Trippier, Sanchez, Vertonghen, Davies; Dier, Dembele; Eriksen, Dele, Son; Kane
Subs: Lloris, Aurier, Alderweireld, Wanyama, Sissoko, Lamela, Lucas
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