Napoli manager Rafael Benitez has recalled Henrique to the starting lineup for their Serie A clash against Sampdoria at the Stadio San Paolo.
Henrique comes into Gli Azzurri's defence with Christian Maggio currently serving a suspension, while the hosts are also without the injured ex-Swansea City duo of Jonathan de Guzman and Michu.
Gokhan Inler and Dries Mertens, who started the Europa League second leg draw against Wolfsburg on Thursday, are among those drop to the bench as Benitez reshuffles his side.
Sampdoria's only injury absentee is defender Fabrizio Cacciatore for the game against the Neapolitans.
Coach Sinisa Mihajlovic has opted for the trio of Eder, Stefano Okaka and Samuel Eto'o up front again for the Blucerchiati.
Samp were held to a goalless draw by Cesena last weekend.
Napoli: Andujar; Henrique, Albiol, Britos, Ghoulam; Jorginho, D.Lopez; Callejon, Gabbiadini, Insigne; Higuain
Sampdoria: Viviano; De Silvestri, Silvestre, Romagnoli, Mesbah; Palombo, Obiang; Eder, Soriano, Eto'o