Preston North End manager Simon Grayson has left new signings Eoin Doyle and Stevie May on the bench for the visit of Derby County to Deepdale.
Last season's top scorer for the Lilywhites, Joe Garner, plays up front, but Jermaine Beckford is likely to be out for several months after undergoing knee surgery this week.
The hosts will also be without Jordan Hugill and Kyel Reid, both of whom picked up knocks in a Lancashire Cup tie this week.
Meanwhile, new signings Jacob Butterfield and Bradley Johnson make their debuts for the Rams, who are still searching for their first league win of the season.
A torn calf muscle keeps George Thorne out of action, while Craig Bryson is still out with a knee injury.
Preston North End: Pickford, Vermijl, Clarke, Huntington, Wright, Cunningham, Welsh, Kilkenny, Johnson, Keane, Garner
Subs: Kirkland, Woods, Browne, Brownhill, Humphrey, Doyle, May
Derby County: Grant, Christie, Keogh, Shackell, Warnock; Baird, Butterfield, Johnson; Ince, Martin, Russell
Subs: Carson, Forsyth, Hendrick, Bent, Weimann, Hanson, Shotton