Sheffield Wednesday defender Reda Johnson will make his first start of the season this afternoon, having recovered from tendonitis.
There are no other changes to the team that started against Leeds last weekend so Chris Maguire and Atdhe Nuhiu are again paired together in attack.
Scott McDonald is handed his first start for Millwall since his summer signing from Middlesbrough.
Andy Keogh and Lee Martin are handed starts as the Championship's bottom side look to score their first goal in the league this season.
Sheffield Wednesday: Kirkland, Buxton, R Johnson, Gardner, Zayatte, Prutton, Coke, Helan, Palmer, Antonio, Nuhiu
Millwall: Bywater, Dunne, Shittu, Lowry, Beevers, Bailey, Martin, Derry, Chaplow, McDonald