England begin their Autumn Internationals on Saturday when they welcome Fiji to Twickenham.
Coach Stuart Lancaster has named a side full of youth, with Leicester Tigers hooker Tom Youngs making his debut.
Meanwhile there are four other changes to the team that drew with South Africa in the third Test in Port Elizabeth five months ago as captain Chris Robshaw, Charlie Sharples, Ugo Monye and Brad Barritt all start.
There are also two uncapped players on the bench in the form of London Wasps back-row Joe Launchbury and Saracens prop Mako Vunipola.
Recent form:
England: LWWLLD
Fiji: WLWLLW
Lineups:
England: Goode, Sharples, Tuilagi, Barritt, Monye; Flood, Care, Marler, Youngs, Cole, Palmer, Parling, Johnson, Robshaw, Waldrom
Replacements: Paice, Wilson, Vunipola, Launchbury, Wood, Youngs, Farrell, Brown
Fiji: Koniferedi; Wara, Goneva, Naqelevuki, Votu; Talebula, Matawalu; Makutu, Veikoso, Manu, Nakawara, Ratuniyarawa, Naikatani, Ravulo, Qera Replacements: Naureure, Samoca, Saulo, Kalou, Ratuva, Bola, Matavesi, Fatiaki
Sports Mole says: England to get their four-Test schedule off to a winning start