Ronald Koeman's side, who are currently second in the table, four points off the summit, will again be without the services of Ansu Fati, Philippe Coutinho and Sergi Roberto this weekend through injury, while Gerard Pique is also unlikely to be available due to a knee problem.
The Catalan giants did not pick up any fresh issues against Huesca on Monday night, though, and it would not be a surprise to see Koeman send the same starting XI onto the field.
Sergio Busquets and Pedri should continue as the midfield two in a 3-4-3 formation, while Koeman is unlikely to make changes in attack, meaning that Antoine Griezmann and Ousmane Dembele should again join Lionel Messi.
There remains speculation surrounding Messi's future, but a recent report claimed that the Argentine is now likely to sign a new long-term contract with Barca.
The 33-year-old is enjoying another fine campaign, scoring 21 times and registering nine assists in 25 La Liga outings, while he has 27 goals in all competitions for the season.
Barcelona possible starting lineup: Ter Stegen; Mingueza, Lenglet, De Jong; Dest, Busquets, Pedri, Alba; Dembele, Messi, Griezmann
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