Both sides will be keen to reach the third round of the FA Cup, when Premier League teams enter the competition, so expect a close tie between two of the lowest-scoring sides in League One.
However, Wigan enter the game with confidence after recording consecutive league wins, and their superior defensive record may see them win by a small margin.
Read more.
Data Analysis
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a Wigan Athletic win with a probability of 53.46%. A draw had a probability of 25.1% and a win for Cambridge United had a probability of 21.46%.
The most likely scoreline for a Wigan Athletic win was 0-1 with a probability of 13.03%. The next most likely scorelines for that outcome were 0-2 (10.39%) and 1-2 (9.46%). The likeliest drawn scoreline was 1-1 (11.85%), while for a Cambridge United win it was 1-0 (7.43%).