Head-to-head record
Previous meetings: 3
RB Leipzig wins: 0
Draws: 0
Liverpool wins: 3
With Leipzig only becoming a dominant force of German football in the past decade, the head-to-head history in this fixture is very modest indeed, with only three previous competitive contests on the record books.
The most recent of those contests came in October 2024, when Liverpool needed a Darwin Nunez tap-in and several top saves from Caoimhin Kelleher to edge out Marco Rose's side 1-0 in the Champions League league phase.
Two meetings also took place in the 2020-21 last 16, both played behind closed doors as coronavirus raged across Europe, and Jurgen Klopp's side schooled their Red Bull counterparts on both occasions.
Indeed, Klopp - who will soon help out at Leipzig as Red Bull's new Global Head of Soccer - masterminded a 4-0 aggregate victory over Julian Nagelsmann's men, following up a 2-0 success in Germany with an identical triumph at Anfield.
The inaugural meeting between Leipzig and Liverpool in February 2021 saw Mohamed Salah and Sadio Mane strike after half time for the Reds, who took on Die Roten Bullen in the midst of their defensive injury crisis; Jordan Henderson and Ozan Kabak played at centre-back that day.
Three weeks later, Liverpool eased into the quarter-finals of Europe's top competition with another 2-0 win inside a near-empty Anfield, but again, they failed to register in the first half of the contest.
As well as an identical scoreline, the second leg also saw identical scorers, as Salah broke the deadlock a few minutes before Mane made sure of the result for Liverpool, who would go on to lose to Real Madrid in the quarter-finals.
Previous meetings
Oct 23, 2024: RB Leipzig 0-1 Liverpool (Champions League League Phase)
Mar 10, 2021: Liverpool 2-0 RB Leipzig (Champions League Round of 16)
Feb 16, 2021: RB Leipzig 0-2 Liverpool (Champions League Round of 16)