The World Cup-winning France striker is a doubt for Tuesday’s encounter at the Etihad Stadium with a calf problem.
Losing one of their headline stars would be a huge blow for Mauricio Pochettino’s side as they bid to overturn a 2-1 first-leg deficit to reach the final in Istanbul.
Meanwhile, PSG have learned midfielder Idrissa Gana Gueye will be suspended for the final if they get through.
The former Everton player received an automatic one-match ban – ruling him out of Tuesday’s game – after his sending off in the first leg against City last week.
UEFA has now announced the suspension has been extended to two matches for “serious rough play” following a disciplinary hearing.
European football’s governing body has also confirmed PSG have been fined £26,000 for delaying the kick-off last week.