Manchester United will be without the services of Marcus Rashford for Thursday's Europa League quarter-final first leg with Sevilla at Old Trafford.
Rashford picked up a groin injury in the latter stages of the clash with Everton last time out, and the Englishman is now facing a period on the sidelines.
Luke Shaw, meanwhile, is still out with the hamstring injury that he suffered against Brentford last week, which could lead to Tyrell Malacia remaining at left-back.
Donny van de Beek, Tom Heaton and Alejandro Garnacho are also definitely out of the contest through injury, but there is positive news on the availability front, with Casemiro set to return after recently been out due to a four-game domestic suspension.
Christian Eriksen also made his return from an ankle injury in the 2-0 win over Everton, handing Red Devils head coach Erik ten Hag another option in midfield.
Anthony Martial has featured off the bench in Man United's last two league games, and the Frenchman is expected to replace Rashford at centre-forward for this match.
Diogo Dalot and Raphael Varane are also set to return to the side following the Everton clash, but Scott McTominay has been ruled out with a training-ground injury, which could see Fred start.
Manchester United possible starting lineup: De Gea; Dalot, Varane, L Martinez, Malacia; Casemiro, Fred, Fernandes; Antony, Martial, Sancho body check tags ::