In a repeat of last year's EFL Cup final, reigning champions Manchester United meet runners-up Newcastle United at Old Trafford for Wednesday's fourth-round affair.
The Red Devils overcame Crystal Palace 3-0 in the third round, while their visitors stunned Manchester City by a goal to nil, and here Sports Mole rounds up the team news for both clubs.
MANCHESTER UNITED vs. NEWCASTLE UNITED
MANCHESTER UNITED
Out: Jadon Sancho (disciplinary), Luke Shaw (muscle), Amad Diallo (knee), Tyrell Malacia (knee), Lisandro Martinez (foot)
Doubtful: Casemiro (ankle), Aaron Wan-Bissaka (thigh)
Sports Mole's predicted XI: Onana; Dalot, Varane, Maguire, Reguilon; Amrabat, Eriksen; Antony, Mount, Garnacho; Hojlund
NEWCASTLE UNITED
Out: Harvey Barnes (ankle), Elliot Anderson (back), Jacob Murphy (shoulder), Lewis Miley (illness), Sandro Tonali (suspended), Sven Botman (knee), Alexander Isak (groin)
Doubtful: None
Sports Mole's predicted XI: Pope; Livramento, Schar, Lascelles, Targett; Willock, Guimaraes, Joelinton; Almiron, Wilson, Gordon
For data analysis of the most likely results, scorelines and more for this match please click here.