AS Roma and Juventus make three changes each to their teams for the Serie A clash at the Stadio Olimpico.
For the home side, Lucas Digne replaces the injured Vasilis Torosidis at left-back to make his debut after arriving from Paris Saint-Germain on a season-long loan this week.
Seydou Keita and Iago Falque also come into the side to replace Leandro Castan and Gervinho as Daniele de Rossi drops back into defence, while Francesco Totti is again on the bench.
Juventus replace the departed Kingsley Coman with Paulo Dybala as the former Palermo man comes in for his first Serie A start as a Juve player.
Martin Caceres takes the place of Andrea Barzagli, while Stefano Sturaro is preferred to Roberto Pereyra in the centre of midfield.
Roma: Szczesny; Florenzi, Manolas, De Rossi, Digne; Keita, Nainggolan, Pjanic, Falque, Salah; Dzeko
Subs: Castan, Iturbe, Totti, Ibarbo, Ljajic, Gyomber, De Sanctis, Gervinho, Maksimovic, Ucan, Anocic, Capradossi
Juventus: Buffon; Caceres, Bonucci, Chiellini, Lichtsteiner; Sturaro, Padoin, Pogba, Evra; Mandzukic, Dybala
Subs: Neto, Rubinho, Barzagli, Rugani, Alex Sandro, Cuadrado, Pereyra, Vitale, Morata, Zaza