Kevin-Prince Boateng has returned to the Schalke 04 starting lineup for the Ruhr derby and will start in an attacking midfield position behind striker Adam Szalai.
For Borussia Dortmund, Pierre-Emerick Aubameyang is preferred on the right flank to replace Jakub Blaszczykowski.
Christian Fuchs is selected by Rafael Benitez for the derby with Julian Draxler providing the pace from the flank.
Schalke: Hildebrand; Fuchs, Howedes, Matip, Uchida; Kolasinac, Neustadter; Aogo, Boateng, Draxler; Szalai
Dortmund: Weidendfeller; Grosskreutz, Subotic, Hummels, Schmelzer; Bender, Sahin; Aubameyang, Mkhitaryan, Reus; Lewandowski