Lewis Hall and Armando Broja have both been handed starts for Chelsea in Wednesday's EFL Cup third-round tie at Manchester City.
With Ben Chilwell out for a number of months with a hamstring injury, 18-year-old Hall is provided with his second start in a Blues at left wing-back.
Meanwhile, Broja makes just his second start down the middle of the attack in a new-look front three alongside Christian Pulisic and Hakim Ziyech.
Denis Zakaria is another player to make his second Chelsea start, joining forces with Mateo Kovacic in midfield, with Ruben Loftus-Cheek seemingly being used at right wing-back unless Marc Cucurella plays at right-back in a four-man defence.
Kalidou Koulibaly returns to the backline after recently recovering from a knee injury, partnering Trevoh Chalobah who continues his run of starts.
While the substitutes' bench is full of first-team regulars, former Arsenal youngster Omari Hutchinson will also hope to make his Chelsea debut.
Manchester City: Ortega; Lewis, Dias, Laporte, Gomez; Rodri, Palmer, Gundogan; Mahrez, Alvarez, Grealish
Subs: Ederson, Phillips, Stones, Ake, Haaland, De Bruyne, Bernardo, Akanji, Foden
Chelsea: Mendy; Chalobah, Koulibaly, Cucurella; Loftus-Cheek, Kovacic, Zakaria, Hall; Ziyech, Broja, Pulisic
Subs: Bettinelli, Azpilicueta, Silva, Gallagher, Mount, Hutchinson, Sterling, Aubameyang, Havertz