Only one of the last seven league meetings between these sides has finished level, and Sevilla are set to be the team which comes out on top this time - repeating their away victory of November to progress to the last eight.
It could be a close-fought affair, given the visitors' general defensive mastery and their depleted front line, but the city will be red again when the final whistle blows on Saturday night.
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Data Analysis
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a Sevilla win with a probability of 45.01%. A win for Real Betis had a probability of 28.76% and a draw had a probability of 26.2%.
The most likely scoreline for a Sevilla win was 0-1 with a probability of 11.32%. The next most likely scorelines for that outcome were 1-2 (9.02%) and 0-2 (8.19%). The likeliest Real Betis win was 1-0 (8.62%), while for a drawn scoreline it was 1-1 (12.46%). The actual scoreline of 2-1 was predicted with a 6.9% likelihood.
