Juve have struggled in the league, while their visitors can boast a perfect top-flight record - with maximum points from their first three matches.
Ahead of their Allianz Stadium showdown, here, Sports Mole rounds up the latest team news from both camps.
Sports Mole's predicted XI: Szczesny; Danilo, Chiellini, Bonucci, Sandro; Cuadrado, Bentancur, Locatelli, Rabiot; Dybala, Morata
Sports Mole's predicted XI: Maignan; Calabria, Kjaer, Tomori, Hernandez; Tonali, Kessie; Saelemaekers, Diaz, Leao; Giroud
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